Are you seeking comprehensive knowledge about medication dose calculation that no one has ever taught you? Our definitive guide is here to provide you with the insights and expertise you need to excel in this critical aspect of healthcare, but if you're looking for a convenient solution to streamline your day-to-day calculations, look no further than our innovative app, Drug Infusion.

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With Drug Infusion, you can unlock the secrets of accurate dose calculation effortlessly. Say goodbye to tedious manual calculations and eliminate the risk of errors. Our advanced drug calculation formulas have been meticulously crafted to ensure precision and safety in every administration. Whether you're in the ICU unit or any healthcare setting, our infusion rate formula and easy-to-use dose calculator will simplify your workflow, saving you valuable time and allowing you to focus on what matters most: your patient's well-being.

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For those who wish to learn the step-by-step process for manually calculating medication doses based on patient weight, please find the guide below.

Step 1: Know the medication concentration

Each medication has a different concentration, which can be found on its medical leaflet. For example, paracetamol has a concentration of 200 mg/mL, which means there are 200 mg in every 1 mL of the medication. Some medications are diluted before use, and in such cases, the concentration of the solution after dilution should be considered. We won't delve deeper into the topic of dilution here, as we will have a dedicated post on how to dilute medications and calculate the concentration after dilution. For the purpose of this step-by-step guide, let's assume a hypothetical solution with a concentration of 1 mg/mL and a volume of 200 mL.

Step 2: Know the medication dose

In the case of the hypothetical medication, the sedation dose ranges from 30 to 200 mcg/kg/h. These values should be consulted in the package insert, books, or other reliable sources. In this case, multiply this dose by the patient's weight in kilograms. Assuming a patient weight of 70 kg and a dose of 30 mcg/kg/h, we will need 30 mcg x 70 kg = 2100 mcg/hour to initiate the sedation for this patient.

Step 3: Calculation of dose in mL/hour

To calculate the dose in mL/hour (as used in the infusion pump), it is necessary to first convert micrograms (mcg) to milligrams (mg). Therefore, 2100 mcg is equivalent to 2.1 mg (divide by 1000). To provide 2.1 mg/hour to the patient, using the hypothetical solution of 1 mg/mL, we apply the following rule of three:

Therefore, we need 2.1 mL/hour of the hypothetical solution with a concentration of 1 mg/mL to provide 2100 mcg/hour, which is equivalent to 30 mcg/kg/hour for a 70 kg patient.

In some cases, it may be necessary to calculate the duration of medication administration at a certain infusion rate. We will teach you how to calculate this time in the bonus section below.

BONUS: Calculation of solution usage time

Using the hypothetical solution at 1 mg/mL with a volume of 200 mL and an infusion rate of 2.1 mL/hour, we can calculate the duration of the solution. Medications can lose their pharmacological properties if diluted in incompatible media or if they take too long to be used after dilution. The calculation of time can be done using the following rule of three:

The hypothetical solution with a volume of 200 mL and an infusion rate of 2.1 mL/hour would last for 95 hours.

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